How long does Botox really work? The science might be different to what you see on your face. Botox is simply a muscle relaxant, reducing how much your skin creases for 3-4 months. Your skin might be better at recovering from creasing if you have more collagen (your younger, use retinol, wear spf etc) do you light get longer out of it. 3-4 months is the norm 💉 #antiwrinkletreatment #botox #antiaging #spf50 #wrinkles #glowingskin #collagen