We all love a holiday feast, and this variant in the POMC gene makes for a large appetite! 🍗 Compared to dogs with no copies of the mutation (NN), dogs with one or two copies of the mutation are more likely to have high food motivation, which can cause them to eat excessively, have a higher body fat percentage, and be more prone to obesity. This variant is found primarily in Labrador and Flat Coated Retrievers.